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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be61c7ab337693755338e06f133751c49e64203e09863600d01e8791219a1c17' 
  AND token = '9tHRgJ3a6zp65BhzNmy6PmPqyAM+Z2/pWhYSTEo8Ppc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}