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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '154ff3f083aa445b748b4fdb553017076fb5e8e8bfd5fa0814cf3a64b88e8f64' 
  AND token = 'FziRWKBHq77PgnCiFPN1SUFWHW6SQZH3HUgwmievxiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}