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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9be287b275fd94098e0f69b1a1b9c3e64004268f89237bcc05b79528d0cf463' 
  AND token = 'QNd1CLYv0Ago3CCAKS9G3wIZBMCLmZ3vdeIaRc3nZ9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}