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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6a515b9d3c55f0f7ab61274ec011967690c752990f62a91fa25711de58f2220' 
  AND token = 'DyiQu8z/CGBt/SiCmm6QBLcV85Ii0HQPc56JLSVTB4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}