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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc109ca31e45bf45e082f53cf087526f1b2563357cbc6e7f2db8f6805da8e7c3' 
  AND token = 'p0yQtgLPgLJBi0eh9wTRWtTlOXKENR40PyI1vwvTtaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}