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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '764f57cefcec5b036303d0ebaa52c7339e2646fb79d26496e7f7f5d77cc6550f' 
  AND token = 'NCEcyeMJyOoijge+UnWIw/zG83XMQm2mKY4dWaEfmys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}