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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed0a0ea2a974bfdc3cd7a3ac15050553a8abb84ca0ac37205023f8f16c09cbc3' 
  AND token = 'ITDzxE+JGxnonbcuBZV2DTD9Dsctrsm0InVkrfkfVG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}