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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd81611b446b9ee25a0f8a1336ab09ed341a1e8fb0c617cfd4f4a9d795969942e' 
  AND token = 'pfnLrTYc/rJHG9qYOMMMavXSS7f5zVZT+IZxcXNyVnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}