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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5182eb614711fca2f86d97024a7a1c4de3e356490f2356c3b9d1a0ccdc75a8e3' 
  AND token = 'NI3JaTzmd0I/NwwD5WJbP8axnAwkKe+iun2cmiGu3G8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}