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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9df2f2980e505cab1e08b42848bc21bbb8f085a8329043f4fb0937fc0b94aca4' 
  AND token = 'lJE7szGE8Y7vT7e++gnxePOfW+rXk2VMIo61Zh4ZjdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}