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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ec08716afc02985d501a6455d16ee53f2d5b899b7f6dfe38f0adb792038df8a' 
  AND token = 'daBvrH4t/4dHX/XAb5pxIr4IUtoS9H+/WcNtmzbmA74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}