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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c69c5d61276f08d48963433db78dbfa37f786c4de09aadebdc53e81cdb8e5f14' 
  AND token = 'EHvK7wI/P6bdJhql7/jnpl0U/RzHjC4RcEb+vnnlhnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}