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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'effac6ba3a52b195ad1030e6eac99b752a776b25f2eedf0041eace79354f9a46' 
  AND token = 'Dp6dLA/2Q2wsvbAjI6DClIsybfgIGeHW3GFg3sFW26I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}