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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49e4394cd90bf12f3dbe83d1e86a2c8460c9b387a173674cd6e83e493dfe33dd' 
  AND token = 'KCWfTy3NkdLeclKtAoGwvTZMkm2xTsTD4RBr9NRkaYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}