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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d3b55fd7af1e8013172d903f303f83e59bb281a0cd69bc3049a55c6bd6b171a' 
  AND token = 'Virw/mdQejkGPyfxmjFjXfPQ53GM1lAbgX4e1P8naGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}