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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fae5065b98e8a8bdbfee1e2c521b542a1fd4943b7aa246652fa1215b8a0bb036' 
  AND token = 'HOS/pqQ8SM9jphotYRPqn/QNyh2o7HLqgAtNuMmFA8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}