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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca3f0ebd4af166bcb8922bb42477caa215e88dc2b09d58ad73e38befd0493687' 
  AND token = 'ILwEqtXvg7eXKJRRSzOGOVwNgqAja59rsE2uUe2ye/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}