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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f1467b3ffdf16b84e4283ba203cd8fb744310a208c05b57984fa2161712766a' 
  AND token = 'POu8iZJ1u5VHbyQy8QtIwz38WYa5n7vBd1o0hjtewJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}