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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9acc78c88ae31e997acfa1f47e9b9328710dd8b42357f4f5b1fc922906f677e1' 
  AND token = 'hcrK/wsbNNg/PJ0kp1d1H8bIEoqX5ZrErdNKC/Oe3PA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}