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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d21521564a6aa33080d45a9306c96afaddd87b97dbe88f331060afbd772ae06' 
  AND token = '8Nsg92ACHFrrshm+Xu++0WT+xrwqqV6IGhGehu6M/vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}