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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82005f2302542ffd95e4893248f72db0bdbfe2ca3d89a9b13b8c6d0f6bb7c6d7' 
  AND token = 'phpnyFFOPX3k/VOyqZSPftHc1eKzz9zKtAMGKVRYGOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}