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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c46df4da336bd5c993ac805e61e8cbb0133cf31ff284808808387f3739e2cbd9' 
  AND token = '/JbnKbCWZcV/LB6Fnt/6DnoxAqv2NgL77vt6KvtWrfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}