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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac6834f3d2456bb8c7ec6ae81aee04bf7d509901322c801ce916e3dc69c9e52b' 
  AND token = 'MJS5cjwO5ZSoizeZWAz3mlTZW4FOZxx+tApPcIhWFG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}