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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '710254336d4270a83cb8f3c213fbd68d0fd9969ec1a19574e1ba150c697640d9' 
  AND token = 'z+4NPFaoFasCeTlvZfXfcn/UDPZZrrMEelMR0GbMyVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}