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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6a9ffc39ca924765fdb0e2e02f327bee041da644418120dd9cf64dde1a47bc8' 
  AND token = 'R1V++E3Xn7Xs5xht1Rv7AeYYbCGzanXzBzsuUQ37iL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}