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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6d0440e8c4ce1e9449ea2c3ab18b217500955274e1782fbc382eecb43a3a848' 
  AND token = 'jyfsOc5R4U+5BLEkb71mYeyhV4fAL11kvvPZ8diYQ9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}