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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd21be28e076a0f7cb450e983c8e2bfa79556f47155736ca977e6d194cf08a484' 
  AND token = 'lkEqNaNZEBN2HBSk6sE3JEDdYHNbjNjX4+FnU5gwKtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}