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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2b89eb97f350128f8b9a70ab36237a4ba0aaa490e062dfaa8593921c767559c' 
  AND token = 'HhpHB/DvMiXnp7QGaxPf2jm1On4ue6zSSdSF2r0h4Mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}