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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47bd058e955c299810e588e4c0e2604c9be36fe18d52adf29a942f5e7218c766' 
  AND token = 'ntwOm0Ne8uBWSe8rCKxo0T8+m7yTQrcIltkvX8qMESc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}