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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '294bfd97a64a8cd1f5681c17528df38a8b6460b6e1e15f1d04748505d9133cf2' 
  AND token = 'AyOKBlnci8BdKO8S9fOZhhPqRFATI0GGHhp1SRPNw5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}