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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c83854b3125d2b54d4902c271cd6343a35c28f505fb3c149f6fd588c251c752d' 
  AND token = '5WAV0A0E2iKnX3zSTgfixLrnWr02/hUdJMUbicB/0r0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}