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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f81cb00d14c842ccf5aa39967dbe6dc6450ba45766222a488e1288ab949013f3' 
  AND token = '2DptNVQGL8XnX7LBlN7Wv4yh3jg6KpY7ere1cpXK8tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}