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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61f46b78489cdefea30ce57d3b6b3833e08c4816bc19ccccd50cde4faf0abce0' 
  AND token = 'Hn2PZw2YKtb/iKK5GWAEKtnPg/9ggKFh2ZL8R1uOrEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}