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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a740c49282e8e9a1b2f349b83ea1a0dbbc194f2fe587c94583f390e7b804ad8f' 
  AND token = 'BZdy/g+o5pQd85m57f3pIOaRsTcAF9CcHjjh/67HUgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}