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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18e88b6c6d934ae11b850c233eb1815784352758c7a90ec1efd548459527f5d3' 
  AND token = 'P/L4y4ZNi/zXbVK7QgFShC4dhqa2xfs8Z5IZcPq1FEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}