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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '505598e3efcafe9dbf2af57b826236c4cf91f5cfe94196aeacb0e1f5f5832723' 
  AND token = 'Heff8qR+BkqiC4t8rPehc3YBiQ/lvnpzfvEzRgEd4Kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}