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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e42b118911d6580efed69a5ee4b691526fcd9cb975ef683e5c12c404b538eb64' 
  AND token = 'l2PbNMLy+LiAkOnjh7UgJvAwOCpAM1bETAJvqN1DzPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}