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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '208f2ed609023fb87f59760c559286ec66772e860b80c8b8cf274c83c10a0d50' 
  AND token = 'Z0O9pWZdxToi8bUBtzgzu9xU4AIcCnckT+a9xxwv7BE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}