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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '861f9567f0ed03452d23d1e6bae7e26dd1b431325aa3fba1815f70ce2de746aa' 
  AND token = 'vWcc2Ea9DOj2+s81bynPFKCSjLlAwVt8SEQbahtLkMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}