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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6db0c84121b6a9bc7e2f14c29c6abd0426e3f731d6a943737101858459c2b426' 
  AND token = 'f+SwU72wMWr57DDUKuHptiBJmWUbZ+Tx92Ll0Qm8tA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}