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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2777d49ac1240604767a95ee6c87b5ff145f95fb8496de4c554835d95f75fd25' 
  AND token = 'gsJ/c63XJKCBOI5a5Is6Ak7DanU3SMNB3hE63knr5FA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}