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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33a08d0f6a48609d413fa934750df10f289f9f14e04cff8ba5c3e2b1dfad17c4' 
  AND token = 'a43D7Sj8AH0xgo9NlV/K2a81Uj/ZU/8lETwdw/VD7Jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}