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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4819a715d505a734c5c1f5b97595768f1089d612f32f4f680fbd8047d26d115d' 
  AND token = 'bvzuNFs8Z4Nnd9oAqZgSqDe9zZF2ZE9XZpPILoy/Zfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}