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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '621a0a8a51096135cb0d4259517dce9a2580aeac77e36df96a58d4bb84a94923' 
  AND token = 'uKyxQkRdkqZYwy/vTzmJgdbgVew5bINCVDe4wpI6Nzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}