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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0df7d897792cac90ee4c04f38afd34a9a900be85c2636c39bf09b4ef5e299881' 
  AND token = '3jBTG02eifq6uf1lp5JdTLpFV4XS1Q8cp1r27ubSWlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}