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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e49dcd141ed28de80713fd01b772ebd11079cfd0e3278c6b48c1263a646e9e01' 
  AND token = 'hQ1iULgjQ0nC1Eq4KW+ih/Papqz8u6bgAk9+96e+AL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}