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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a86c62b39e76495f7619946986bd7963b9548fa2afdd36deb7eb012325ef798' 
  AND token = 'Mj7vfV5EdSmYRfT81423iSfQZx9nNSicKmB1S2+hAeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}