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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7bdc6b07f9ee8e96c3f37848f903b526d0c85512afe0c1090bbcc35bd880c74' 
  AND token = 'lRP0pnnyqSCfI7eWq22b2Rd8OYMGJ+met4s1G2z8vUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}