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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce29bc84a007a250b743636e700f19f2804b3ccabb56a9b091e555a5e0952691' 
  AND token = '/dsPQRxiil+lcNW79g5/xorpSb78noGfTc5B5TKtaHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}