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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22da62b57d8ae160f69f45f2faf3996f0b25d92127731f63af375ea09bab6021' 
  AND token = 'zvUF+aA5IkM/Z76cIZEwIn4XbkVPDuByd1nK3W3Ic+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}